Diagnosis of the above microorganisms, using Nucleic Acid Technology (NAT) based detection systems, has relied on analysis using swab samples, which often require the assistance of a physician for sampling and often involves painful invasive procedures. Thus, a noninvasive method of screening for the presence of these pathogens is by the collection of urine samples.
This will promote an increase in screening and contribute to controlling the spread of Chlamydia and gonorrhoea infections.
Available NAT systems, developed for C. trachomatis and Neisseria gonorrhoea diagnostics all include procedures using urine samples.
However, nucleic acid preparation from urine samples has generally been associated with cumbersome manual procedures involving much hands-on time compared to the processing of swab samples, and the presence of amplification inhibitors present in urine.