Month: May 2021

nordiag

A haplotype map of the human genome.

  May 27, 2021
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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems provide bacteria and archaea with adaptive immunity against viruses and plasmids by using CRISPR RNAs (crRNAs) to guide the silencing of invading nucleic acids. We show here that in a subset of these systems, the mature crRNA that is […]

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nordiag

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

  May 25, 2021
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation. The Cancer Genome Atlas (TCGA) pilot project aims to assess the value of large-scale multi-dimensional analysis of these molecular characteristics in human cancer and to provide the data […]

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