A framework for variation discovery and genotyping using next-generation DNA sequencing data.
Recent advances in sequencing technology make it possible to comprehensively catalog genetic variation in population samples, creating a foundation for understanding human disease, ancestry and evolution. The amounts of raw data produced are prodigious, and many computational steps are required to translate this output into high-quality variant calls. We present a unified analytic framework to discover and genotype variation among multiple samples simultaneously that achieves sensitive and specific results across five sequencing technologies and three distinct, canonical experimental designs.
Our process includes (i) initial read mapping; (ii) local realignment around indels; (iii) base quality score recalibration; (iv) SNP discovery and genotyping to find all potential variants; and (v) machine learning to separate true segregating variation from machine artifacts common to next-generation sequencing technologies. We here discuss the application of these tools, instantiated in the Genome Analysis Toolkit, to deep whole-genome, whole-exome capture and multi-sample low-pass (∼4×) 1000 Genomes Project datasets.
Green RNA Lysis Kit 50 |
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| GREENE1-RNA | Next Advance | 50pack | EUR 216 |
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Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
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Green RNA Lysis Kit 250 |
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| GREENE5-RNA | Next Advance | 250pack | EUR 685.2 |
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Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
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Pink RNA Lysis Kit 50 |
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| PINKE1-RNA | Next Advance | 50pack | EUR 213.6 |
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Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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Pink RNA Lysis Kit 250 |
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| PINKE5-RNA | Next Advance | 250pack | EUR 673.2 |
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Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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Red RNA Lysis Kit 50 |
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| REDE1-RNA | Next Advance | 50pack | EUR 230.4 |
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Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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Red RNA Lysis Kit 250 |
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| REDE5-RNA | Next Advance | 250pack | EUR 746.4 |
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Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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YELLOW RNA Lysis Kit 50 |
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| YELLOWE1-RNA | Next Advance | 50pack | EUR 230.4 |
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Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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YELLOW RNA Lysis Kit 250 |
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| YELLOWE5-RNA | Next Advance | 250pack | EUR 748.8 |
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Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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5E Navy RNA Lysis Kit 100 |
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| NAVY5E100-RNA | Next Advance | 100pack | EUR 543.6 |
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Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
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5E Navy RNA Lysis Kit 20 |
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| NAVY5E20-RNA | Next Advance | 20pack | EUR 183.6 |
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Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
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Navy RINO RNA Lysis Kit 50 |
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| NAVYR1-RNA | Next Advance | 50pack | EUR 242.4 |
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Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free. |
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Navy RINO RNA Lysis Kit 250 |
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| NAVYR5-RNA | Next Advance | 250pack | EUR 799.2 |
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Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free. |
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5E GREEN RNA Lysis Kit 100 |
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| GREEN5E100-RNA | Next Advance | 100pack | EUR 463.2 |
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Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
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5E GREEN RNA Lysis Kit 20 |
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| GREEN5E20-RNA | Next Advance | 20pack | EUR 165.6 |
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Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
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Green RINO RNA Lysis Kit 50 |
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| GREENR1-RNA | Next Advance | 50pack | EUR 220.8 |
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Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free. |
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Green RINO RNA Lysis Kit 250 |
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| GREENR5-RNA | Next Advance | 250pack | EUR 704.4 |
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Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free. |
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5E PINK RNA Lysis Kit 100 |
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| PINK5E100-RNA | Next Advance | 100pack | EUR 456 |
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Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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5E PINK RNA Lysis Kit 20 |
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| PINK5E20-RNA | Next Advance | 20pack | EUR 163.2 |
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Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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Pink RINO RNA Lysis Kit 50 |
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| PINKR1-RNA | Next Advance | 50pack | EUR 217.2 |
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Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
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Pink RINO RNA Lysis Kit 250 |
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| PINKR5-RNA | Next Advance | 250pack | EUR 691.2 |
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Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
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5E RED RNA Lysis Kit 100 |
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| RED5E100-RNA | Next Advance | 100pack | EUR 514.8 |
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Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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5E RED RNA Lysis Kit 20 |
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| RED5E20-RNA | Next Advance | 20pack | EUR 177.6 |
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Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
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Red RINO RNA Lysis Kit 50 |
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| REDR1-RNA | Next Advance | 50pack | EUR 234 |
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Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
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Red RINO RNA Lysis Kit 250 |
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| REDR5-RNA | Next Advance | 250pack | EUR 765.6 |
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Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
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YELLOW RINO RNA Lysis Kit 50 |
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| YELLOWR1-RNA | Next Advance | 50pack | EUR 238.8 |
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Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
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YELLOW RINO RNA Lysis Kit 250 |
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| YELLOWR5-RNA | Next Advance | 250pack | EUR 787.2 |
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Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
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Exosomal RNA Extraction Kit |
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| P200R,-part-of-P200 | 101Bio | - | Ask for price |
100 BP DNA LADDER, 500UL PER KIT |
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| M-DNA-100BP | CORNING | 1/pk | EUR 87.6 |
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Description: Bioscience Mol Bio; DNA Ladder |
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1 KB DNA LADDER, 500UL PER KIT |
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| M-DNA-1KB | CORNING | 1/pk | EUR 84 |
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Description: Bioscience Mol Bio; DNA Ladder |
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Custom production of antibodies in 5 Rats using customer supplied antigen (std 63 days protocol) |
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| RAT-5 | Alpha Diagnostics | 1 | EUR 1365.6 |
Dr. P Kit-Isolation of RNA, DNA and Protein from the same piece of tissue simultaneously |
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| K2021010 | Biochain | 1 kit | EUR 506.4 |
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Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
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Set of 8 Sulfur Oil Standards in Base Oil 20 100 grams |
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| DSS8-SET | Scientific Laboratory Supplies | EACH | EUR 636.12 |
Kin17 DNA And RNA Binding Protein (KIN) Antibody |
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| 20-abx113374 | Abbexa |
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Kin17 DNA And RNA Binding Protein (KIN) Protein |
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| 20-abx260971 | Abbexa |
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Kin17 DNA And RNA Binding Protein (KIN) Antibody |
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| abx234575-100ug | Abbexa | 100 ug | EUR 610.8 |
Cross match determination (FCXM) |
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| FCXM-100T | ImmunoStep | 100 test | EUR 806.18 |
Cross match determination (FCXM) |
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| FCXM-25T | ImmunoStep | 25 test | EUR 412.04 |
Cross match determination (FCXM) |
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| FCXMPU | ImmunoStep | 0,5 mg | EUR 620.04 |
Set of 8 Sulfur in Oil Standards in no.2 DieselFuel 100 grams |
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| SDFS-SET | Scientific Laboratory Supplies | EACH | EUR 657.78 |
ICP-MS Set of 2 Memory Test Solutions |
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| CL-MEM-SET | Scientific Laboratory Supplies | EACH | EUR 467.4 |
Groundwater and Wastewater Pollution Control Check Standard (includes WP-11 and MN-4) |
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| AM-SET | Scientific Laboratory Supplies | EACH | EUR 355.68 |
Human Brain Genomic DNA |
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| X11001-1 | EpiGentek | 10 ul | EUR 77 |
Human Brain Genomic DNA |
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| X11001 | EpiGentek |
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Groundwater and Wastewater Pollution Control Check Standard (includes WP-15N WP-3 and MN-6) |
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| TM-SET | Scientific Laboratory Supplies | EACH | EUR 417.24 |
Total RNA from Rat Normal Tissue: Brain |
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| R1434035-50 | Biochain | 50 ug | EUR 182.4 |
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Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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Viral DNA / RNA Kit |
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| 20-abx098090 | Abbexa |
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Viral DNA / RNA Kit |
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| abx098872-50rxns | Abbexa | 50 rxns | EUR 444 |
DNA / RNA Damage Antibody |
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| abx440040-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx442569-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx442850-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx443130-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx443410-100ug | Abbexa | 100 ug | EUR 644.4 |
DNA / RNA Damage Antibody |
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| abx443691-100ug | Abbexa | 100 ug | EUR 678 |
DNA / RNA Damage Antibody |
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| abx443972-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx444253-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx444534-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| 20-abx444884 | Abbexa |
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DNA / RNA Damage Antibody |
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| abx440321-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx440602-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx440883-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx441164-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx441445-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx441726-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx442007-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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| abx442288-100ug | Abbexa | 100 ug | EUR 661.2 |
EZBlock? Universal Protease and Phosphatase Inhibitor Cocktail |
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| K283-set | Biovision | EUR 744 | |
Human Kin17 DNA And RNA Binding Protein (KIN) ELISA Kit |
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| abx388159-96tests | Abbexa | 96 tests | EUR 1093.2 |
MAX LIFE Gene Analyzer - Fluorometer for DNA, RNA and Protein |
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| H100 | GeneOn | 1 pcs | Ask for price |
Genomic DNA from Rat Normal Tissue: Brain |
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| D1434035 | Biochain | 100 ug | EUR 338.4 |
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Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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EZCell? Cell Stimulation and Protein Transport Inhibitor Cocktail (500X) |
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| K931-set | Biovision | EUR 444 | |
EZBlock? Universal Protease and Phosphatase Inhibitor Cocktail , EDTA-Free |
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| K284-set | Biovision | EUR 751.2 | |
Nanosoft Clipping Tool, Set of 4 grid clipping tools with C-Clip Bottoming tool and Tool Rack |
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| M-CEM-NS-CLT-Set | MiTeGen | 1 UNIT | EUR 900 |
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Description: Nanosoft Clipping Tool, Set of 4 grid clipping tools with C-Clip Bottoming tool and Tool Rack |
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Match cell/stpr QS/GLP10mm 3.5ml |
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| CEL2052 | Scientific Laboratory Supplies | 1PR | EUR 363.66 |
Match cell/lid QS LP10mm 1.4ml |
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| CEL2120 | Scientific Laboratory Supplies | 1PR | EUR 274.74 |
ELISA Microplate Washer Automated (#MPW-30) bottle set (3 bottles and cap assembly) |
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| MPW-30-SET | Alpha Diagnostics | 1 | EUR 489.6 |
Total RNA from Rat Normal Tissue: Brain, cerebellum |
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| R1434039-50 | Biochain | 50 ug | EUR 182.4 |
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Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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ICP Environmental EPA Set |
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| EPA-SET | Scientific Laboratory Supplies | EACH | EUR 1512.78 |
BenzNuclease DNA and RNA Nuclease (Ultra Pure, Protease Free) Recombinant Protein |
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| 11-552 | ProSci | 50KU | EUR 481.2 |
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Description: BenzNuclease DNA and RNA Nuclease (Ultra Pure, Protease Free) Recombinant Protein |
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Human DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) |
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| 1-CSB-EP897095HU | Cusabio |
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Description: Recombinant Human DNA-directed RNA polymerases I and III subunit RPAC2(POLR1D) expressed in E.coli |
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NUCLEAZOR, DNA & RNA Decontaminant Spray |
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| N5000-025 | GenDepot | 250 ml | EUR 162 |
Human DNA-directed DNA/RNA polymerase mu (POLM) |
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| 1-CSB-EP889065HU | Cusabio |
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Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in E.coli |
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Human DNA-directed DNA/RNA polymerase mu (POLM) |
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| 1-CSB-BP889065HU | Cusabio |
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Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Baculovirus |
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Human DNA-directed DNA/RNA polymerase mu (POLM) |
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| 1-CSB-YP889065HU | Cusabio |
|
|
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Description: Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM) expressed in Yeast |
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Recombinant human DNA-directed DNA/RNA polymerase mu |
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| P2815 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA-directed DNA/RNA polymerase mu |
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Total RNA from Alzheimer's Disease: Brain |
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| R1236035Alz-50 | Biochain | 50 ug | EUR 421.2 |
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Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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1 each of 6.5 mm, 12 mm, 16 mm, 20 mm heights |
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| EZStage-Set | MiTeGen | 4 UNITS | EUR 340 |
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Description: 1 each of 6.5 mm, 12 mm, 16 mm, 20 mm heights |
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US EPA Method 200.7 (Rev.3.3) and SW-846 Method 6010 (3rd ed.) |
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| MIXSTD-SET | Scientific Laboratory Supplies | EACH | EUR 595.08 |
Brain and Acute Leukemia, Cytoplamatic |
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| PR27238 | Neuromics | 2 ug | EUR 229.2 |
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC3 (RPAB3) Antibody |
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| 20-abx149876 | Abbexa |
|
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody |
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| 20-abx135780 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody |
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| 20-abx007835 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| 20-abx001458 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| 20-abx121663 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (RPAB1) Antibody |
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| 20-abx119102 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| 20-abx114604 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| abx028042-400ul | Abbexa | 400 ul | EUR 627.6 |
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| abx028042-80l | Abbexa | 80 µl | EUR 343.2 |
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| abx036186-100ug | Abbexa | 100 ug | EUR 469.2 |
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC2 (RPAB2) Antibody |
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| 20-abx217855 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (RPAB4) Antibody |
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| 20-abx217857 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody |
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| 20-abx304890 | Abbexa |
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody |
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| 20-abx304897 | Abbexa |
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StemBoost? YPAC Cocktail Set (1000X), Sterile-Filtered |
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| K871-set | Biovision | EUR 1149.6 | |
ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) |
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| KTE100871-48T | Abbkine | 48T | EUR 398.4 |
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Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) |
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| KTE100871-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
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Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) |
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| KTE100871-96T | Abbkine | 96T | EUR 646.8 |
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Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ISOLATE II RNA/DNA/Protein Kit |
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| BIO-52085 | Bioline | 50 preps | Ask for price |
ISOLATE II RNA/DNA/Protein Kit |
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| BIO-52085/S | Bioline | Sample | Ask for price |
ISOLATE II FFPE RNA/DNA Kit |
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| BIO-52087 | Bioline | 50 Preps | Ask for price |
RNA/DNA Purification Kit (Magnetic Bead) |
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| DA0623 | Daan Gene | 32 test/kit | Ask for price |
96-well Viral DNA/RNA Kit |
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| K1417-1 | Biovision | EUR 470.4 | |
96-well Viral DNA/RNA Kit |
|||
| K1417-4 | Biovision | EUR 1227.6 | |
Silicon Column for DNA/RNA Extraction |
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| GR238011 | Genorise Scientific | Pack of 100 | EUR 170.4 |
Monoclonal antibody for DNA/RNA Damage |
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| SMC-155C | Stressmarq | 0.025mg | EUR 228 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
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Monoclonal antibody for DNA/RNA Damage |
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| SMC-155D | Stressmarq | 0.1mg | EUR 398.4 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
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Monoclonal antibody for DNA/RNA Damage |
|||
| SMC-155D-A390 | Stressmarq | 0.1mg | EUR 454.8 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390. |
|||
Monoclonal antibody for DNA/RNA Damage |
|||
| SMC-155D-A488 | Stressmarq | 0.1mg | EUR 453.6 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488. |
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Monoclonal antibody for DNA/RNA Damage |
|||
| SMC-155D-A565 | Stressmarq | 0.1mg | EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565. |
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Monoclonal antibody for DNA/RNA Damage |
|||
| SMC-155D-A594 | Stressmarq | 0.1mg | EUR 453.6 |
|
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594. |
|||
Monoclonal antibody for DNA/RNA Damage |
|||
| SMC-155D-A633 | Stressmarq | 0.1mg | EUR 453.6 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633. |
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Monoclonal antibody for DNA/RNA Damage |
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| SMC-155D-A655 | Stressmarq | 0.1mg | EUR 453.6 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655. |
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Monoclonal antibody for DNA/RNA Damage |
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| SMC-155D-A680 | Stressmarq | 0.1mg | EUR 453.6 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680. |
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Monoclonal antibody for DNA/RNA Damage |
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| SMC-155D-A700 | Stressmarq | 0.1mg | EUR 453.6 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700. |
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Monoclonal antibody for DNA/RNA Damage |
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| SMC-155D-ALP | Stressmarq | 0.1mg | EUR 446.4 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase. |
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Monoclonal antibody for DNA/RNA Damage |
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| SMC-155D-APC | Stressmarq | 0.1mg | EUR 452.4 |
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Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC. |
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The 1982 revised criteria for the classification of systemic lupus erythematosus
The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification. The 1982 revised criteria include fluorescence antinuclear antibody and antibody to native DNA and Sm antigen. Some criteria involving the same organ systems were aggregated into single criteria.
Raynaud’s phenomenon and alopecia were not included in the 1982 revised criteria because of low sensitivity and specificity. The new criteria were 96% sensitive and 96% specific when tested with SLE and control patient data gathered from 18 participating clinics. When compared with the 1971 criteria, the 1982 revised criteria showed gains in sensitivity and specificity.
Translating the histone code
Chromatin, the physiological template of all eukaryotic genetic information, is subject to a diverse array of posttranslational modifications that largely impinge on histone amino termini, thereby regulating access to the underlying DNA. Distinct histone amino-terminal modifications can generate synergistic or antagonistic interaction affinities for chromatin-associated proteins, which in turn dictate dynamic transitions between transcriptionally active or transcriptionally silent chromatin states.
The combinatorial nature of histone amino-terminal modifications thus reveals a “histone code” that considerably extends the information potential of the genetic code. We propose that this epigenetic marking system represents a fundamental regulatory mechanism that has an impact on most, if not all, chromatin-templated processes, with far-reaching consequences for cell fate decisions and both normal and pathological development.
Genomic sequencing
Unique DNA sequences can be determined directly from mouse genomic DNA. A denaturing gel separates by size mixtures of unlabeled DNA fragments from complete restriction and partial chemical cleavages of the entire genome. These lanes of DNA are transferred and UV-crosslinked to nylon membranes. Hybridization with a short 32P-labeled single-stranded probe produces the image of a DNA sequence “ladder” extending from the 3′ or 5′ end of one restriction site in the genome. Numerous different sequences can be obtained from a single membrane by reprobing.
Each band in these sequences represents 3 fg of DNA complementary to the probe. Sequence data from mouse immunoglobulin heavy chain genes from several cell types are presented. The genomic sequencing procedures are applicable to the analysis of genetic polymorphisms, DNA methylation at deoxycytidines, and nucleic acid-protein interactions at single nucleotide resolution.
A new method for sequencing DNA
DNA can be sequenced by a chemical procedure that breaks a terminally labeled DNA molecule partially at each repetition of a base. The lengths of the labeled fragments then identify the positions of that base. We describe reactions that cleave DNA preferentially at guanines, at adenines, at cytosines and thymines equally, and at cytosines alone.
When the products of these four reactions are resolved by size, by electrophoresis on a polyacrylamide gel, the DNA sequence can be read from the pattern of radioactive bands. The technique will permit sequencing of at least 100 bases from the point of labeling.
Genome sequencing in microfabricated high-density picolitre reactors
The proliferation of large-scale DNA-sequencing projects in recent years has driven a search for alternative methods to reduce time and cost. Here we describe a scalable, highly parallel sequencing system with raw throughput significantly greater than that of state-of-the-art capillary electrophoresis instruments. The apparatus uses a novel fibre-optic slide of individual wells and is able to sequence 25 million bases, at 99% or better accuracy, in one four-hour run.
To achieve an approximately 100-fold increase in throughput over current Sanger sequencing technology, we have developed an emulsion method for DNA amplification and an instrument for sequencing by synthesis using a pyrosequencing protocol optimized for solid support and picolitre-scale volumes. Here we show the utility, throughput, accuracy and robustness of this system by shotgun sequencing and de novo assembly of the Mycoplasma genitalium genome with 96% coverage at 99.96% accuracy in one run of the machine.
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers
A series of plasmid vectors containing the multiple cloning site (MCS7) of M13mp7 has been constructed. In one of these vectors a kanamycin-resistance marker has been inserted into the center of the symmetrical MCS7 to yield a restriction-site-mobilizing element (RSM).
The drug-resistance marker can be cleaved out of this vector with any of the restriction enzymes that recognize a site of the flanking sequences of the RSM to generate an RSM with either various sticky ends or blunt ends. These fragments can be used for insertion mutagenesis of any target molecule with compatible restriction sites. Insertion mutants are selected by their resistance to kanamycin.
When the drug-resistance marker is removed with PstI, a small in-frame insertion can be generated. In addition, two new MCSs having single restriction sites have been formed by altering the symmetrical structure of MCS7. The resulting plasmids pUC8 and pUC9 allow one to clone doubly digested restriction fragments separately with both orientations in respect to the lac promoter. The terminal sequences of any DNA cloned in these plasmids can be characterized using the universal M13 primers.
DNAJB14 Polyclonal Antibody |
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| 30628-100ul | SAB | 100ul | EUR 302.4 |
DNAJB14 Polyclonal Antibody |
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| 30628-50ul | SAB | 50ul | EUR 224.4 |
DNAJB14 Polyclonal Antibody |
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| A66234-020 | EpiGentek | 20 ul | EUR 117.7 |
DNAJB14 Polyclonal Antibody |
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| A66234-050 | EpiGentek | 50 ul | EUR 302.5 |
DNAJB14 Polyclonal Antibody |
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| A66234-100 | EpiGentek | 100 ul | EUR 423.5 |
DNAJB14 Polyclonal Antibody |
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| A72739-050 | EpiGentek | 50 ul | EUR 302.5 |
DNAJB14 Polyclonal Antibody |
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| A72739-100 | EpiGentek | 100 ul | EUR 423.5 |
DNAJB14 Polyclonal Antibody |
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| A66234 | EpiGentek |
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DNAJB14 Polyclonal Antibody |
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| A72739 | EpiGentek |
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DNAJB14 siRNA |
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| 20-abx914343 | Abbexa |
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DNAJB14 siRNA |
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| 20-abx914344 | Abbexa |
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DNAJB14 Polyclonal Conjugated Antibody |
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| C30628 | SAB | 100ul | EUR 476.4 |
DNAJB14 Antibody, HRP conjugated |
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| 1-CSB-PA819454LB01HU | Cusabio |
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Description: A polyclonal antibody against DNAJB14. Recognizes DNAJB14 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
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DNAJB14 Antibody, FITC conjugated |
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| 1-CSB-PA819454LC01HU | Cusabio |
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Description: A polyclonal antibody against DNAJB14. Recognizes DNAJB14 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
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DNAJB14 Antibody, Biotin conjugated |
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| 1-CSB-PA819454LD01HU | Cusabio |
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Description: A polyclonal antibody against DNAJB14. Recognizes DNAJB14 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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DNAJB14 Blocking Peptide |
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| DF12198-BP | Affbiotech | 1mg | EUR 234 |
DNAJB14 cloning plasmid |
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| CSB-CL819454HU-10ug | Cusabio | 10ug | EUR 279.6 |
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Description: A cloning plasmid for the DNAJB14 gene. |
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DNAJB14 Rabbit pAb |
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| A4990-100ul | Abclonal | 100 ul | EUR 369.6 |
DNAJB14 Rabbit pAb |
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| A4990-200ul | Abclonal | 200 ul | EUR 550.8 |
DNAJB14 Rabbit pAb |
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| A4990-20ul | Abclonal | 20 ul | EUR 219.6 |
DNAJB14 Rabbit pAb |
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| A4990-50ul | Abclonal | 50 ul | EUR 267.6 |
DNAJB14 Polyclonal Antibody, HRP Conjugated |
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| A66235-050 | EpiGentek | 50 ul | EUR 302.5 |
DNAJB14 Polyclonal Antibody, HRP Conjugated |
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| A66235-100 | EpiGentek | 100 ul | EUR 423.5 |
DNAJB14 Polyclonal Antibody, FITC Conjugated |
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| A66236-050 | EpiGentek | 50 ul | EUR 302.5 |
DNAJB14 Polyclonal Antibody, FITC Conjugated |
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| A66236-100 | EpiGentek | 100 ul | EUR 423.5 |
DNAJB14 Polyclonal Antibody, Biotin Conjugated |
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| A66237-050 | EpiGentek | 50 ul | EUR 302.5 |
DNAJB14 Polyclonal Antibody, Biotin Conjugated |
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| A66237-100 | EpiGentek | 100 ul | EUR 423.5 |
DNAJB14 Polyclonal Antibody, HRP Conjugated |
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| A66235 | EpiGentek |
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DNAJB14 Polyclonal Antibody, FITC Conjugated |
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| A66236 | EpiGentek |
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DNAJB14 Polyclonal Antibody, Biotin Conjugated |
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| A66237 | EpiGentek |
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Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST p-form |
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| GST-ANTI-3 | Detroit R&D | 50 uL | EUR 336 |
Human DNAJB14 shRNA Plasmid |
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| 20-abx962706 | Abbexa |
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Mouse DNAJB14 shRNA Plasmid |
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| 20-abx977260 | Abbexa |
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DNAJB14 ELISA KIT|Human |
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| EF009156 | Lifescience Market | 96 Tests | EUR 826.8 |
DNAJB14 Recombinant Protein (Mouse) |
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| RP129476 | ABM | 100 ug | Ask for price |
DNAJB14 Recombinant Protein (Rat) |
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| RP198299 | ABM | 100 ug | Ask for price |
DNAJB14 Recombinant Protein (Human) |
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| RP009529 | ABM | 100 ug | Ask for price |
Dnajb14 ORF Vector (Rat) (pORF) |
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| ORF066101 | ABM | 1.0 ug DNA | EUR 607.2 |
DNAJB14 ORF Vector (Human) (pORF) |
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| ORF003177 | ABM | 1.0 ug DNA | EUR 114 |
Dnajb14 ORF Vector (Mouse) (pORF) |
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| ORF043160 | ABM | 1.0 ug DNA | EUR 607.2 |
DNAJB14 sgRNA CRISPR Lentivector set (Human) |
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| K0614501 | ABM | 3 x 1.0 ug | EUR 406.8 |
Dnajb14 sgRNA CRISPR Lentivector set (Rat) |
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| K6216401 | ABM | 3 x 1.0 ug | EUR 406.8 |
Dnajb14 sgRNA CRISPR Lentivector set (Mouse) |
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| K4586901 | ABM | 3 x 1.0 ug | EUR 406.8 |
DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody |
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| 20-abx112129 | Abbexa |
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DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody |
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| 20-abx003806 | Abbexa |
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DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody |
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| abx232446-100ug | Abbexa | 100 ug | EUR 577.2 |
DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody |
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| 20-abx302018 | Abbexa |
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DNAJB14 sgRNA CRISPR Lentivector (Human) (Target 1) |
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| K0614502 | ABM | 1.0 ug DNA | EUR 184.8 |
DNAJB14 sgRNA CRISPR Lentivector (Human) (Target 2) |
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| K0614503 | ABM | 1.0 ug DNA | EUR 184.8 |
DNAJB14 sgRNA CRISPR Lentivector (Human) (Target 3) |
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| K0614504 | ABM | 1.0 ug DNA | EUR 184.8 |
Dnajb14 sgRNA CRISPR Lentivector (Rat) (Target 1) |
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| K6216402 | ABM | 1.0 ug DNA | EUR 184.8 |
Dnajb14 sgRNA CRISPR Lentivector (Rat) (Target 2) |
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| K6216403 | ABM | 1.0 ug DNA | EUR 184.8 |
Dnajb14 sgRNA CRISPR Lentivector (Rat) (Target 3) |
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| K6216404 | ABM | 1.0 ug DNA | EUR 184.8 |
Dnajb14 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
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| K4586902 | ABM | 1.0 ug DNA | EUR 184.8 |
Dnajb14 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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| K4586903 | ABM | 1.0 ug DNA | EUR 184.8 |
Dnajb14 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
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| K4586904 | ABM | 1.0 ug DNA | EUR 184.8 |
DNAJB14 Protein Vector (Human) (pPB-C-His) |
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| PV012705 | ABM | 500 ng | EUR 394.8 |
DNAJB14 Protein Vector (Human) (pPB-N-His) |
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| PV012706 | ABM | 500 ng | EUR 394.8 |
DNAJB14 Protein Vector (Human) (pPM-C-HA) |
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| PV012707 | ABM | 500 ng | EUR 394.8 |
DNAJB14 Protein Vector (Human) (pPM-C-His) |
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| PV012708 | ABM | 500 ng | EUR 394.8 |
DNAJB14 Protein Vector (Mouse) (pPB-C-His) |
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| PV172638 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Mouse) (pPB-N-His) |
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| PV172639 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Mouse) (pPM-C-HA) |
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| PV172640 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Mouse) (pPM-C-His) |
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| PV172641 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Rat) (pPB-C-His) |
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| PV264402 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Rat) (pPB-N-His) |
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| PV264403 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Rat) (pPM-C-HA) |
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| PV264404 | ABM | 500 ng | EUR 723.6 |
DNAJB14 Protein Vector (Rat) (pPM-C-His) |
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| PV264405 | ABM | 500 ng | EUR 723.6 |
DNAJB14 3'UTR Luciferase Stable Cell Line |
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| TU006138 | ABM | 1.0 ml | EUR 2799.6 |
Dnajb14 3'UTR Luciferase Stable Cell Line |
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| TU203509 | ABM | 1.0 ml | Ask for price |
Dnajb14 3'UTR GFP Stable Cell Line |
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| TU253509 | ABM | 1.0 ml | Ask for price |
Dnajb14 3'UTR GFP Stable Cell Line |
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| TU155250 | ABM | 1.0 ml | Ask for price |
Dnajb14 3'UTR Luciferase Stable Cell Line |
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| TU105250 | ABM | 1.0 ml | Ask for price |
DNAJB14 3'UTR GFP Stable Cell Line |
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| TU056138 | ABM | 1.0 ml | EUR 2799.6 |
DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody (HRP) |
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| 20-abx308795 | Abbexa |
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DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody (FITC) |
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| 20-abx308796 | Abbexa |
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DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody (Biotin) |
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| 20-abx308797 | Abbexa |
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Human DnaJ Homolog Subfamily B Member 14 (DNAJB14) ELISA Kit |
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| abx386930-96tests | Abbexa | 96 tests | EUR 1093.2 |
DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
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| K0614505 | ABM | 3 x 1.0 ug | EUR 451.2 |
Bovine DnaJ homolog subfamily B member 14, DNAJB14 ELISA KIT |
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| ELI-31942b | Lifescience Market | 96 Tests | EUR 1113.6 |
Human DnaJ homolog subfamily B member 14, DNAJB14 ELISA KIT |
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| ELI-26399h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse DnaJ homolog subfamily B member 14, Dnajb14 ELISA KIT |
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| ELI-08275m | Lifescience Market | 96 Tests | EUR 1038 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
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| K6216405 | ABM | 3 x 1.0 ug | EUR 451.2 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
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| K4586905 | ABM | 3 x 1.0 ug | EUR 451.2 |
DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
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| K0614506 | ABM | 1.0 ug DNA | EUR 200.4 |
DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
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| K0614507 | ABM | 1.0 ug DNA | EUR 200.4 |
DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
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| K0614508 | ABM | 1.0 ug DNA | EUR 200.4 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
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| K6216406 | ABM | 1.0 ug DNA | EUR 200.4 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
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| K6216407 | ABM | 1.0 ug DNA | EUR 200.4 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
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| K6216408 | ABM | 1.0 ug DNA | EUR 200.4 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
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| K4586906 | ABM | 1.0 ug DNA | EUR 200.4 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
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| K4586907 | ABM | 1.0 ug DNA | EUR 200.4 |
Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
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| K4586908 | ABM | 1.0 ug DNA | EUR 200.4 |
Anti-Anti-SEPT6 antibody antibody |
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| STJ11100949 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
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Anti-Anti-SEPT9 Antibody antibody |
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| STJ111369 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
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Anti-Anti-SEPT11 Antibody antibody |
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| STJ111530 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT4 Antibody antibody |
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| STJ112276 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
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Anti-Anti-MARCH9 Antibody antibody |
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| STJ112609 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT2 Antibody antibody |
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| STJ25475 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT5 Antibody antibody |
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| STJ25477 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
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Anti-Anti-SEPT8 Antibody antibody |
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| STJ25479 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Anti-Anti-SEPT2 Antibody antibody |
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| STJ28365 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT7 Antibody antibody |
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| STJ28963 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
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Anti-Anti-SEPT1 antibody antibody |
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| STJ119580 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
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Anti-Anti-SEPT12 Antibody antibody |
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| STJ117759 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Anti-Anti-MARCH6 Antibody antibody |
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| STJ118549 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-MARCH6 Antibody antibody |
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| STJ118550 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-MARCH7 Antibody antibody |
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| STJ118752 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT3 Antibody antibody |
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| STJ118990 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT11 Antibody antibody |
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| STJ113941 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT11 Antibody antibody |
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| STJ114081 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT5 Antibody antibody |
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| STJ114819 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
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Anti-Anti-MARCH8 Antibody antibody |
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| STJ114828 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT7 Antibody antibody |
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| STJ116214 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
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Anti-Anti-SEPT8 Antibody antibody |
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| STJ117206 | St John's Laboratory | 100 µl | EUR 332.4 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Anti-Anti-DDB1 Antibody |
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| A00333 | BosterBio | 100uL | EUR 546 |
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Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6777.36 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 663.31 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 896.16 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3672.72 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| 4-AEA465Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
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ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody) |
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| ELK8071 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
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Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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Anti-H4K20me1 Antibody |
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| CI1005 | BosterBio | 100ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
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Anti-H4K20me3 Antibody |
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| CI1011 | BosterBio | 100ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
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Anti-TIP5 Antibody |
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| CI1016 | BosterBio | 100ul | EUR 589.2 |
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Description: Rabbit Polyclonal TIP5 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human, Mouse. |
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Anti-H4K8ac Antibody |
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| CI1021 | BosterBio | 100ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
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Anti-MYH11 Antibody |
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| CI1028 | BosterBio | 100ul | EUR 589.2 |
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Description: Rabbit Polyclonal MYH11 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human. |
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Anti-Ski3 Antibody |
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| CI1031 | BosterBio | 150ug/50ul | EUR 589.2 |
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Description: Rabbit Polyclonal Ski3 Antibody. Validated in ChIP, ChIP-qPCR, IF, IHC, WB and tested in Human. |
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Anti-Ski8 Antibody |
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| CI1032 | BosterBio | 150ug/60ul | EUR 589.2 |
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Description: Rabbit Polyclonal Ski8 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Drosophila, Human. |
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Anti-H4K5,8,12ac Antibody |
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| CI1033 | BosterBio | 50ug/66ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K5,8,12ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse. |
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Anti-H4K5,8,12,16ac Antibody |
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| CI1035 | BosterBio | 50ug/66ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K5,8,12,16ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse. |
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Anti-H4K5ac Antibody |
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| CI1036 | BosterBio | 50ug/28ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human, Mouse. |
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Anti-H4K20me1 Antibody |
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| CI1039 | BosterBio | 50ug/25ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
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Anti-MeCP2 Antibody |
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| CI1047 | BosterBio | 50ug/42ul | EUR 589.2 |
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Description: Rabbit Polyclonal MeCP2 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human. |
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Anti-H4K20me3 Antibody |
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| CI1050 | BosterBio | 50ug/47ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse. |
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Anti-H3K27me3 Antibody |
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| CI1056 | BosterBio | 50ug/34ul | EUR 589.2 |
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Description: Rabbit Polyclonal H3K27me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Arabidopsis, Drosophila, Human, Mouse, Rat, Schistosoma, Zebrafish. |
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Anti-MBD1 Antibody |
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| CI1058 | BosterBio | 50ug/72ul | EUR 589.2 |
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Description: Rabbit Polyclonal MBD1 Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human, Mouse. |
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Anti-p53 Antibody |
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| CI1060 | BosterBio | 50ug/50ul | EUR 589.2 |
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Description: Rabbit Polyclonal p53 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IHC, WB and tested in Human. |
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Anti-H4K8ac Antibody |
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| CI1066 | BosterBio | 50ug/41ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse. |
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Anti-H4pan Antibody |
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| CI1069 | BosterBio | 50ug/44ul | EUR 589.2 |
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Description: Rabbit Polyclonal H4pan Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human. |
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Anti-H2AK5ac Antibody |
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| CI1078 | BosterBio | 50ug/ 54ul | EUR 589.2 |
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Description: Rabbit Polyclonal H2AK5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human. |
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Antibody Anti-cKit |
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| CKITACPO | ImmunoStep | 0,1 mg | EUR 379.8 |
anti- LIN28B antibody |
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| FNab04785 | FN Test | 100µg | EUR 658.5 |
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Description: Antibody raised against LIN28B |
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