Integrated genomic analyses of ovarian carcinoma

A catalogue of molecular aberrations that cause ovarian cancer is critical for developing and deploying therapies that will improve patients’ lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumours. Here we report that high-grade serous ovarian cancer is characterized by TP53 mutations in almost all tumours (96%); low prevalence but statistically recurrent somatic mutations in nine further genes including NF1, BRCA1, BRCA2, RB1 and CDK12; 113 significant focal DNA copy number aberrations; and promoter methylation events involving 168 genes.

Analyses delineated four ovarian cancer transcriptional subtypes, three microRNA subtypes, four promoter methylation subtypes and a transcriptional signature associated with survival duration, and shed new light on the impact that tumours with BRCA1/2 (BRCA1 or BRCA2) and CCNE1 aberrations have on survival. Pathway analyses suggested that homologous recombination is defective in about half of the tumours analysed, and that NOTCH and FOXM1 signalling are involved in serous ovarian cancer pathophysiology.

Rapid isolation of high molecular weight plant DNA.

A method is presented for the rapid isolation of high molecular weight plant DNA (50,000 base pairs or more in length) which is free of contaminants which interfere with complete digestion by restriction endonucleases. The procedure yields total cellular DNA (i.e. nuclear, chloroplast, and mitochondrial DNA). The technique is ideal for the rapid isolation of small amounts of DNA from many different species and is also useful for large scale isolations.

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid.

Construction and characterization of a class of multicopy plasmid cloning vehicles containing the replication system of miniplasmid P15A are described. The constructed plasmids have cleavage sites within antibiotic resistance genes for a variety of commonly employed site-specific endonucleases, permitting convenient use of the insertional inactivation procedure for the selection of clones that contain hybrid DNA molecules.

Although the constructed plasmids showed DNA sequence homology with the ColE1 plasmid within the replication region, were amplifiable by chloramphenicol or spectinomycin, required DNA polymerase I for replication, and shared other replication properties with ColE1, they were nevertheless compatible with ColE1. P15A-derived plasmids were not self-transmissible and were mobilized poorly by Hfr strains; however, mobilization was complemented by the presence of a ColE1 plasmid within the same cell.

Genome-wide insertional mutagenesis of Arabidopsis thaliana

Over 225,000 independent Agrobacterium transferred DNA (T-DNA) insertion events in the genome of the reference plant Arabidopsis thaliana have been created that represent near saturation of the gene space. The precise locations were determined for more than 88,000 T-DNA insertions, which resulted in the identification of mutations in more than 21,700 of the approximately 29,454 predicted Arabidopsis genes.

Genome-wide analysis of the distribution of integration events revealed the existence of a large integration site bias at both the chromosome and gene levels. Insertion mutations were identified in genes that are regulated in response to the plant hormone ethylene.

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

The Cancer Genome Atlas Network recently cataloged recurrent genomic abnormalities in glioblastoma multiforme (GBM). We describe a robust gene expression-based molecular classification of GBM into Proneural, Neural, Classical, and Mesenchymal subtypes and integrate multidimensional genomic data to establish patterns of somatic mutations and DNA copy number. Aberrations and gene expression of EGFR, NF1, and PDGFRA/IDH1 each define the Classical, Mesenchymal, and Proneural subtypes, respectively.

Gene signatures of normal brain cell types show a strong relationship between subtypes and different neural lineages. Additionally, response to aggressive therapy differs by subtype, with the greatest benefit in the Classical subtype and no benefit in the Proneural subtype. We provide a framework that unifies transcriptomic and genomic dimensions for GBM molecular stratification with important implications for future studies.

The International HapMap Project.

The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain.

An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association between them, in DNA samples from populations with ancestry from parts of Africa, Asia and Europe. The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance our ability to choose targets for therapeutic intervention.

Sequence and organization of the human mitochondrial genome

The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III, ATPase subunit 6, cytochrome b and eight other predicted protein coding genes have been located. The sequence shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs.

Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences.

In 2001 and 2002, we published two papers (Bioinformatics, 17, 282-283, Bioinformatics, 18, 77-82) describing an ultrafast protein sequence clustering program called cd-hit.

This program can efficiently cluster a huge protein database with millions of sequences. However, the applications of the underlying algorithm are not limited to only protein sequences clustering, here we present several new programs using the same algorithm including cd-hit-2d, cd-hit-est and cd-hit-est-2d. Cd-hit-2d compares two protein datasets and reports similar matches between them; cd-hit-est clusters a DNA/RNA sequence database and cd-hit-est-2d compares two nucleotide datasets

. All these programs can handle huge datasets with millions of sequences and can be hundreds of times faster than methods based on the popular sequence comparison and database search tools, such as BLAST.

DNAJB14 Polyclonal Antibody
30628-100ul	SAB	100ul	EUR 302.4

DNAJB14 Polyclonal Antibody
30628-50ul	SAB	50ul	EUR 224.4

DNAJB14 Polyclonal Antibody
A66234-020	EpiGentek	20 ul	EUR 117.7

DNAJB14 Polyclonal Antibody
A66234-050	EpiGentek	50 ul	EUR 302.5

DNAJB14 Polyclonal Antibody
A66234-100	EpiGentek	100 ul	EUR 423.5

DNAJB14 Polyclonal Antibody
A72739-050	EpiGentek	50 ul	EUR 302.5

DNAJB14 Polyclonal Antibody
A72739-100	EpiGentek	100 ul	EUR 423.5

DNAJB14 Polyclonal Antibody
A66234	EpiGentek	EUR 684.66 EUR 117.70 EUR 302.50 EUR 423.50	100 µg 20 ul 50 ul 100 ul

DNAJB14 Polyclonal Antibody
A72739	EpiGentek	EUR 302.50 EUR 423.50	50 ul 100 ul

DNAJB14 siRNA
20-abx914343	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

DNAJB14 siRNA
20-abx914344	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

DNAJB14 Polyclonal Conjugated Antibody
C30628	SAB	100ul	EUR 476.4

DNAJB14 Antibody, HRP conjugated
1-CSB-PA819454LB01HU	Cusabio	EUR 380.40 EUR 402.00	100ug 50ug

Description: A polyclonal antibody against DNAJB14. Recognizes DNAJB14 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

DNAJB14 Antibody, FITC conjugated
1-CSB-PA819454LC01HU	Cusabio	EUR 380.40 EUR 402.00	100ug 50ug

Description: A polyclonal antibody against DNAJB14. Recognizes DNAJB14 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DNAJB14 Antibody, Biotin conjugated
1-CSB-PA819454LD01HU	Cusabio	EUR 380.40 EUR 402.00	100ug 50ug

Description: A polyclonal antibody against DNAJB14. Recognizes DNAJB14 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

DNAJB14 Blocking Peptide
DF12198-BP	Affbiotech	1mg	EUR 234

DNAJB14 cloning plasmid
CSB-CL819454HU-10ug	Cusabio	10ug	EUR 279.6

Description: A cloning plasmid for the DNAJB14 gene.

DNAJB14 Rabbit pAb
A4990-100ul	Abclonal	100 ul	EUR 369.6

DNAJB14 Rabbit pAb
A4990-200ul	Abclonal	200 ul	EUR 550.8

DNAJB14 Rabbit pAb
A4990-20ul	Abclonal	20 ul	EUR 219.6

DNAJB14 Rabbit pAb
A4990-50ul	Abclonal	50 ul	EUR 267.6

DNAJB14 Polyclonal Antibody, HRP Conjugated
A66235-050	EpiGentek	50 ul	EUR 302.5

DNAJB14 Polyclonal Antibody, HRP Conjugated
A66235-100	EpiGentek	100 ul	EUR 423.5

DNAJB14 Polyclonal Antibody, FITC Conjugated
A66236-050	EpiGentek	50 ul	EUR 302.5

DNAJB14 Polyclonal Antibody, FITC Conjugated
A66236-100	EpiGentek	100 ul	EUR 423.5

DNAJB14 Polyclonal Antibody, Biotin Conjugated
A66237-050	EpiGentek	50 ul	EUR 302.5

DNAJB14 Polyclonal Antibody, Biotin Conjugated
A66237-100	EpiGentek	100 ul	EUR 423.5

DNAJB14 Polyclonal Antibody, HRP Conjugated
A66235	EpiGentek	EUR 684.66 EUR 302.50 EUR 423.50	100 µg 50 ul 100 ul

DNAJB14 Polyclonal Antibody, FITC Conjugated
A66236	EpiGentek	EUR 684.66 EUR 302.50 EUR 423.50	100 µg 50 ul 100 ul

DNAJB14 Polyclonal Antibody, Biotin Conjugated
A66237	EpiGentek	EUR 684.66 EUR 302.50 EUR 423.50	100 µg 50 ul 100 ul

Polyclonal Goat anti-GST α-form
GST-ANTI-1	Detroit R&D	50 uL	EUR 336

Polyclonal Goat anti-GST μ-form
GST-ANTI-2	Detroit R&D	50 uL	EUR 336

Polyclonal Goat anti-GST p-form
GST-ANTI-3	Detroit R&D	50 uL	EUR 336

Human DNAJB14 shRNA Plasmid
20-abx962706	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Mouse DNAJB14 shRNA Plasmid
20-abx977260	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

DNAJB14 ELISA KIT\|Human
EF009156	Lifescience Market	96 Tests	EUR 826.8

DNAJB14 Recombinant Protein (Mouse)
RP129476	ABM	100 ug	Ask for price

DNAJB14 Recombinant Protein (Rat)
RP198299	ABM	100 ug	Ask for price

DNAJB14 Recombinant Protein (Human)
RP009529	ABM	100 ug	Ask for price

Dnajb14 ORF Vector (Rat) (pORF)
ORF066101	ABM	1.0 ug DNA	EUR 607.2

DNAJB14 ORF Vector (Human) (pORF)
ORF003177	ABM	1.0 ug DNA	EUR 114

Dnajb14 ORF Vector (Mouse) (pORF)
ORF043160	ABM	1.0 ug DNA	EUR 607.2

DNAJB14 sgRNA CRISPR Lentivector set (Human)
K0614501	ABM	3 x 1.0 ug	EUR 406.8

Dnajb14 sgRNA CRISPR Lentivector set (Rat)
K6216401	ABM	3 x 1.0 ug	EUR 406.8

Dnajb14 sgRNA CRISPR Lentivector set (Mouse)
K4586901	ABM	3 x 1.0 ug	EUR 406.8

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody
20-abx112129	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody
20-abx003806	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody
abx232446-100ug	Abbexa	100 ug	EUR 577.2

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody
20-abx302018	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

DNAJB14 sgRNA CRISPR Lentivector (Human) (Target 1)
K0614502	ABM	1.0 ug DNA	EUR 184.8

DNAJB14 sgRNA CRISPR Lentivector (Human) (Target 2)
K0614503	ABM	1.0 ug DNA	EUR 184.8

DNAJB14 sgRNA CRISPR Lentivector (Human) (Target 3)
K0614504	ABM	1.0 ug DNA	EUR 184.8

Dnajb14 sgRNA CRISPR Lentivector (Rat) (Target 1)
K6216402	ABM	1.0 ug DNA	EUR 184.8

Dnajb14 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6216403	ABM	1.0 ug DNA	EUR 184.8

Dnajb14 sgRNA CRISPR Lentivector (Rat) (Target 3)
K6216404	ABM	1.0 ug DNA	EUR 184.8

Dnajb14 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4586902	ABM	1.0 ug DNA	EUR 184.8

Dnajb14 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K4586903	ABM	1.0 ug DNA	EUR 184.8

Dnajb14 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K4586904	ABM	1.0 ug DNA	EUR 184.8

DNAJB14 Protein Vector (Human) (pPB-C-His)
PV012705	ABM	500 ng	EUR 394.8

DNAJB14 Protein Vector (Human) (pPB-N-His)
PV012706	ABM	500 ng	EUR 394.8

DNAJB14 Protein Vector (Human) (pPM-C-HA)
PV012707	ABM	500 ng	EUR 394.8

DNAJB14 Protein Vector (Human) (pPM-C-His)
PV012708	ABM	500 ng	EUR 394.8

DNAJB14 Protein Vector (Mouse) (pPB-C-His)
PV172638	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Mouse) (pPB-N-His)
PV172639	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Mouse) (pPM-C-HA)
PV172640	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Mouse) (pPM-C-His)
PV172641	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Rat) (pPB-C-His)
PV264402	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Rat) (pPB-N-His)
PV264403	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Rat) (pPM-C-HA)
PV264404	ABM	500 ng	EUR 723.6

DNAJB14 Protein Vector (Rat) (pPM-C-His)
PV264405	ABM	500 ng	EUR 723.6

DNAJB14 3'UTR Luciferase Stable Cell Line
TU006138	ABM	1.0 ml	EUR 2799.6

Dnajb14 3'UTR Luciferase Stable Cell Line
TU203509	ABM	1.0 ml	Ask for price

Dnajb14 3'UTR GFP Stable Cell Line
TU253509	ABM	1.0 ml	Ask for price

Dnajb14 3'UTR GFP Stable Cell Line
TU155250	ABM	1.0 ml	Ask for price

Dnajb14 3'UTR Luciferase Stable Cell Line
TU105250	ABM	1.0 ml	Ask for price

DNAJB14 3'UTR GFP Stable Cell Line
TU056138	ABM	1.0 ml	EUR 2799.6

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody (HRP)
20-abx308795	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody (FITC)
20-abx308796	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14) Antibody (Biotin)
20-abx308797	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human DnaJ Homolog Subfamily B Member 14 (DNAJB14) ELISA Kit
abx386930-96tests	Abbexa	96 tests	EUR 1093.2

DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K0614505	ABM	3 x 1.0 ug	EUR 451.2

Bovine DnaJ homolog subfamily B member 14, DNAJB14 ELISA KIT
ELI-31942b	Lifescience Market	96 Tests	EUR 1113.6

Human DnaJ homolog subfamily B member 14, DNAJB14 ELISA KIT
ELI-26399h	Lifescience Market	96 Tests	EUR 988.8

Mouse DnaJ homolog subfamily B member 14, Dnajb14 ELISA KIT
ELI-08275m	Lifescience Market	96 Tests	EUR 1038

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K6216405	ABM	3 x 1.0 ug	EUR 451.2

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K4586905	ABM	3 x 1.0 ug	EUR 451.2

DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K0614506	ABM	1.0 ug DNA	EUR 200.4

DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K0614507	ABM	1.0 ug DNA	EUR 200.4

DNAJB14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K0614508	ABM	1.0 ug DNA	EUR 200.4

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K6216406	ABM	1.0 ug DNA	EUR 200.4

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6216407	ABM	1.0 ug DNA	EUR 200.4

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K6216408	ABM	1.0 ug DNA	EUR 200.4

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K4586906	ABM	1.0 ug DNA	EUR 200.4

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K4586907	ABM	1.0 ug DNA	EUR 200.4

Dnajb14 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K4586908	ABM	1.0 ug DNA	EUR 200.4

Anti-Anti-SEPT6 antibody antibody
STJ11100949	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody
STJ111369	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody
STJ111530	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT4 Antibody antibody
STJ112276	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody
STJ112609	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT2 Antibody antibody
STJ25475	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT5 Antibody antibody
STJ25477	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody
STJ25479	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody
STJ28365	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT7 Antibody antibody
STJ28963	St John's Laboratory	100 µl	EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT1 antibody antibody
STJ119580	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT12 Antibody antibody
STJ117759	St John's Laboratory	100 µl	EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody
STJ118549	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-MARCH6 Antibody antibody
STJ118550	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-MARCH7 Antibody antibody
STJ118752	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT3 Antibody antibody
STJ118990	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT11 Antibody antibody
STJ113941	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT11 Antibody antibody
STJ114081	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT5 Antibody antibody
STJ114819	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody
STJ114828	St John's Laboratory	100 µl	EUR 332.4

Anti-Anti-SEPT7 Antibody antibody
STJ116214	St John's Laboratory	100 µl	EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody
STJ117206	St John's Laboratory	100 µl	EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-DDB1 Antibody
A00333	BosterBio	100uL	EUR 546
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit
AEA465Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 6777.36

Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit
AEA465Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 663.31

Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit
AEA465Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 896.16

Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit
AEA465Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 3672.72

Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit
4-AEA465Hu	Cloud-Clone	EUR 6837.60 EUR 3613.20 EUR 896.40	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells

Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)
ELK8071	ELK Biotech	1 plate of 96 wells	EUR 518.4

Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-H4K20me1 Antibody
CI1005	BosterBio	100ul	EUR 589.2
Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-H4K20me3 Antibody
CI1011	BosterBio	100ul	EUR 589.2
Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-TIP5 Antibody
CI1016	BosterBio	100ul	EUR 589.2
Description: Rabbit Polyclonal TIP5 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human, Mouse.

Anti-H4K8ac Antibody
CI1021	BosterBio	100ul	EUR 589.2
Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-MYH11 Antibody
CI1028	BosterBio	100ul	EUR 589.2
Description: Rabbit Polyclonal MYH11 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human.

Anti-Ski3 Antibody
CI1031	BosterBio	150ug/50ul	EUR 589.2
Description: Rabbit Polyclonal Ski3 Antibody. Validated in ChIP, ChIP-qPCR, IF, IHC, WB and tested in Human.

Anti-Ski8 Antibody
CI1032	BosterBio	150ug/60ul	EUR 589.2
Description: Rabbit Polyclonal Ski8 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Drosophila, Human.

Anti-H4K5,8,12ac Antibody
CI1033	BosterBio	50ug/66ul	EUR 589.2
Description: Rabbit Polyclonal H4K5,8,12ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse.

Anti-H4K5,8,12,16ac Antibody
CI1035	BosterBio	50ug/66ul	EUR 589.2
Description: Rabbit Polyclonal H4K5,8,12,16ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Human, Mouse.

Anti-H4K5ac Antibody
CI1036	BosterBio	50ug/28ul	EUR 589.2
Description: Rabbit Polyclonal H4K5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human, Mouse.

Anti-H4K20me1 Antibody
CI1039	BosterBio	50ug/25ul	EUR 589.2
Description: Rabbit Polyclonal H4K20me1 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-MeCP2 Antibody
CI1047	BosterBio	50ug/42ul	EUR 589.2
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in ChIP, ChIP-qPCR, WB and tested in Human.

Anti-H4K20me3 Antibody
CI1050	BosterBio	50ug/47ul	EUR 589.2
Description: Rabbit Polyclonal H4K20me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse.

Anti-H3K27me3 Antibody
CI1056	BosterBio	50ug/34ul	EUR 589.2
Description: Rabbit Polyclonal H3K27me3 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IF, IHC, WB and tested in Arabidopsis, Drosophila, Human, Mouse, Rat, Schistosoma, Zebrafish.

Anti-MBD1 Antibody
CI1058	BosterBio	50ug/72ul	EUR 589.2
Description: Rabbit Polyclonal MBD1 Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human, Mouse.

Anti-p53 Antibody
CI1060	BosterBio	50ug/50ul	EUR 589.2
Description: Rabbit Polyclonal p53 Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, Flow Cytometry, IHC, WB and tested in Human.

Anti-H4K8ac Antibody
CI1066	BosterBio	50ug/41ul	EUR 589.2
Description: Rabbit Polyclonal H4K8ac Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, IF, IHC, WB and tested in Human, Mouse.

Anti-H4pan Antibody
CI1069	BosterBio	50ug/44ul	EUR 589.2
Description: Rabbit Polyclonal H4pan Antibody. Validated in ChIP, ChIP-qPCR, Flow Cytometry, WB and tested in Human.

Anti-H2AK5ac Antibody
CI1078	BosterBio	50ug/ 54ul	EUR 589.2
Description: Rabbit Polyclonal H2AK5ac Antibody. Validated in ChIP, ChIP-qPCR, ChIP-seq, IHC, WB and tested in Human.

Antibody Anti-cKit
CKITACPO	ImmunoStep	0,1 mg	EUR 379.8

anti- LIN28B antibody
FNab04785	FN Test	100µg	EUR 658.5

Description: Antibody raised against LIN28B

anti- LIN41 antibody
FNab04787	FN Test	100µg	EUR 658.5

Description: Antibody raised against LIN41

anti- LIN7A antibody
FNab04788	FN Test	100µg	EUR 702

Description: Antibody raised against LIN7A

anti- LIN7B antibody
FNab04789	FN Test	100µg	EUR 658.5

Description: Antibody raised against LIN7B

anti- LIN7C antibody
FNab04790	FN Test	100µg	EUR 658.5

Description: Antibody raised against LIN7C

anti- LIN9 antibody
FNab04791	FN Test	100µg	EUR 606.3

Description: Antibody raised against LIN9

anti- LINGO1 antibody
FNab04792	FN Test	100µg	EUR 658.5

Description: Antibody raised against LINGO1

anti- LIPA antibody
FNab04793	FN Test	100µg	EUR 606.3

Description: Antibody raised against LIPA

anti- LIPC antibody
FNab04794	FN Test	100µg	EUR 606.3

Description: Antibody raised against LIPC

anti- LIPH antibody
FNab04795	FN Test	100µg	EUR 606.3

Description: Antibody raised against LIPH

anti- LIPI antibody
FNab04796	FN Test	100µg	EUR 702

Description: Antibody raised against LIPI

anti- LITAF antibody
FNab04798	FN Test	100µg	EUR 606.3

Description: Antibody raised against LITAF

anti- LKB1 antibody
FNab04802	FN Test	100µg	EUR 658.5

Description: Antibody raised against LKB1

anti- LMAN1 antibody
FNab04803	FN Test	100µg	EUR 658.5

Description: Antibody raised against LMAN1

Tags: antigenes, bromides, enzymes, Isotype, Lenti, Medium, microRNA, Monoclonal, pcr, Polyclonal, Recombinant, rna, Secondairy, Serum, Tag, Vector

NorDiag Biotech Plasmid and DNA purification